Upscale utilizes
proven mechanical
seal technology and
provides the
following features:
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Technical
Specifications |
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- Upscale® acrylic columns are designed to meet the requirements for large scale purification of biological molecules using low pressure liquid chromatography techniques.
- Upscale® columns consist of an acrylic tube protected by an acrylic jacket, a base plate and an adjustable piston. The piston range allows the user to select a variety of bed heights and volumes.
- The base plate and piston are equipped with a flow distribution system, composed of an anti-jetting device and radial distribution channels equipped with a 20µm frit.
- Upscale® columns feature an efficient flow distribution system which ensures uniform flow of liquid onto the surface of the packing material and out of the column.
- The sealing systems at the lower and upper portion of the column have been designed to minimize dead volume which may trap micro-organisms, retain contaminating substances and/or dilute the sample. All connections have a sanitary design.
- The column is easily packed with a few simple adjustments.
- The piston range is set and pressure is applied on the upper seal by simply operating two handles, which reduces the time required for set-up of the column.
- Upscale® columns are composed of biocompatible materials and will withstand solutions commonly used in low pressure liquid chromatography.
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